Association between NOD2/CARD15 gene polymorphisms and Crohn's disease in Chinese Zhuang patients

Table 5 Clinical characteristics of Crohn’s disease patients in Guangxi with and without P268S mutations

Phenotype	n	P268S+	P268S-	P value
Age of onset				aP
≤ 40 years	45	8 (17.8)	37 (82.2)
> 40 years	53	2 (3.8)	51 (96.2)
Location				NS
Ileum	58	6 (10.3)	52 (89.7)
Colon/ileocolon	40	4 (10.0)	36 (90.0)
Gender				NS
Male	51	7 (13.7)	44 (86.3)
Female	47	3 (6.4)	44 (93.6)
Ethnic groups				NS
Han	50	4 (8.0)	46 (92.0)
Zhuang	48	6 (12.5)	42 (87.5)
Comorbidities				NS
Luminal stenosis	31	4 (12.9)	27 (87.1)
No luminal stenosis	67	6 (9.0)	61 (91.0)
Severity				NS
Severe	42	3 (7.1)	39 (92.9)
Mild-moderate	56	7 (12.5)	49 (87.5)

NS: No significance. P268S+ Mutant P268S; P268S- Wild-type P268S.

^aP < 0.05 using Fisher's exact test.