Association between NOD2/CARD15 gene polymorphisms and Crohn's disease in Chinese Zhuang patients

Table 4 Distribution of genotype and allele frequencies of mutations in Crohn’s disease and ulcerative colitis patients compared with healthy controls in the Guangxi Han population n (%)

Mutant	Genotype	Allele	Control	CD		UC
					P value		P value
P268S					bP1		NS1
	CC		78 (100.0)	46 (92.0)		48 (96.0)
	CT		0 (0.0)	4 (8.0)		2 (4.0)
	TT		0 (0.0)	0 (0.0)		0 (0.0)
		T	0 (0.0)	4 (4.0)	dP2	2 (2.0)	NS2
JW1					NS1		NS1
	CC		78 (100.0)	50 (100.0)		50 (100.0)
	CT		0 (0.0)	0 (0.0)		0 (0.0)
	TT		0 (0.0)	0 (0.0)		0 (0.0)
		T	0 (0.0)	0 (0.0)	NS2	0 (0.0)	NS2
N852S					NS1		NS1
	AA		78 (100.0)	50 (100.0)		50 (100.0)
	AG		0 (0.0)	0 (0.0)		0 (0.0)
	GG		0 (0.0)	0 (0.0)		0 (0.0)
		G	0 (0.0)	0 (0.0)	NS2	0 (0.0)	NS2

¹Comparisons of genotype frequencies;

²Comparisons of allele frequencies.

^bP < 0.05 vs control using Fisher's exact test;

^dP < 0.05 vs control using Fisher's exact test. CD: Crohn’s disease; UC: Ulcerative colitis; NS: No significance.