Association between NOD2/CARD15 gene polymorphisms and Crohn's disease in Chinese Zhuang patients

Table 3 Distribution of genotype and allele frequencies of mutations in Crohn’s disease and ulcerative colitis patients compared with healthy controls in the Guangxi Zhuang population n (%)

Mutant	Genotype	Allele	Control	CD		UC
					P value		P value
P268S					aP1		NS1
	CC		71 (98.6)	42 (87.5)		54 (100.0)
	CT		1 (1.4)	6 (12.5)		0 (0.0)
	TT		0 (0.0)	0 (0.0)		0 (0.0)
		T	1 (0.7)	6 (6.2)	cP2	0 (0.0)	NS2
JW1					NS1		NS1
	CC		72 (100.0)	48 (100.0)		54 (100.0)
	CT		0 (0.0)	0 (0.0)		0 (0.0)
	TT		0 (0.0)	0 (0.0)		0 (0.0)
		T	0 (0.0)	0 (0.0)	NS2	0 (0.0)	NS2
N852S					NS1		NS1
	AA		72 (100.0)	48 (100.0)		54 (100.0)
	AG		0 (0.0)	0 (0.0)		0 (0.0)
	GG		0 (0.0)	0 (0.0)		0 (0.0)
		G	0 (0.0)	0 (0.0)	NS2	0 (0.0)	NS2

¹Comparisons of genotype frequencies;

²Comparisons of allele frequencies.

^aP < 0.05 vs control using Fisher's exact test;

^cP < 0.05 vs control using Fisher's exact test. CD: Crohn’s disease; UC: Ulcerative colitis; NS: No significance.