MT1M and MT1G promoter methylation as biomarkers for hepatocellular carcinoma

doi:10.3748/wjg.v20.i16.4723

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Apr 28, 2014 (publication date) through Nov 4, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Apr 28, 2014; 20(16): 4723-4729
Published online Apr 28, 2014. doi: 10.3748/wjg.v20.i16.4723

Table 6 Sensitivity and specificity of gene sets for hepatocellular carcinoma detection in normal controls group

No.	Gene	TP/FN	FP/TN	Sensitivity (%)TP/(TP+FN)	Specificity (%)TN/(TN+FP)
1	MT1M	59/62	2/29	48.8	93.5
2	MT1G	85/36	4/27	70.2	87.1
3	MT1M/MT1G	110/11	5/26	90.9	83.9

Sensitivity (%), TP/(TP + FN) and specificity (%), TN/(TN + FP) of each gene set were calculated and plotted. MT1M/MT1G, MT1M or MT1G promoter methylation. TP: True positive; FN: False negative; FP: False positive; TN: True negative; MT1M: Metallothionein 1M; MT1G: Metallothionein 1G.

Citation: Ji XF, Fan YC, Gao S, Yang Y, Zhang JJ, Wang K. MT1M and MT1G promoter methylation as biomarkers for hepatocellular carcinoma. World J Gastroenterol 2014; 20(16): 4723-4729
URL: https://www.wjgnet.com/1007-9327/full/v20/i16/4723.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i16.4723