MT1M and MT1G promoter methylation as biomarkers for hepatocellular carcinoma

doi:10.3748/wjg.v20.i16.4723

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Apr 28, 2014 (publication date) through Oct 2, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Apr 28, 2014; 20(16): 4723-4729
Published online Apr 28, 2014. doi: 10.3748/wjg.v20.i16.4723

Table 5 Sensitivity and specificity of gene sets for hepatitis B virus (+) hepatocellular carcinoma detection in chronic hepatitis B group

No.	Marker	TP/FN	FP/TN	Sensitivity (%)TP/(TP + FN)	Specificity (%)TN/(TN + FP)
1	AFP	56/44	14/23	56.0	62.1
2	MT1M	50/50	2/35	50.0	94.6
3	MT1G	69/31	6/31	69.0	83.8
4	MT1M/MT1G	90/10	7/30	90.0	81.1

Sensitivity (%), TP/(TP + FN) and specificity (%), TN/(TN + FP) of each gene set were calculated and plotted. MT1M/MT1G, MT1M or MT1G promoter methylation. TP: True positive; FN: False negative; FP: False positive; TN: True negative.

Citation: Ji XF, Fan YC, Gao S, Yang Y, Zhang JJ, Wang K. MT1M and MT1G promoter methylation as biomarkers for hepatocellular carcinoma. World J Gastroenterol 2014; 20(16): 4723-4729
URL: https://www.wjgnet.com/1007-9327/full/v20/i16/4723.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i16.4723