Protective effect of glutamine on intestinal injury and bacterial community in rats exposed to hypobaric hypoxia environment

doi:10.3748/wjg.v20.i16.4662

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Apr 28, 2014 (publication date) through Feb 8, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Apr 28, 2014; 20(16): 4662-4674
Published online Apr 28, 2014. doi: 10.3748/wjg.v20.i16.4662

Table 2 Effect of hypoxia and glutamine on intestinal villi and mucosa

Group	Height of villi (μm)	Thickness of mucosa (μm)	Villous area (μm²)
Control	750.800 ± 13.530	283.900 ± 6.096	813.900 ± 56.500
HH	378.300 ± 20.310^b	203.700 ± 2.758^b	342.200 ± 39.550^b
HG	736.300 ± 20.640^d	233.700 ± 3.989^d	827.400 ± 35.160^d

The height of the intestinal villi (P < 0.001) and the thickness of the mucosa (P < 0.001) and villous area (P < 0.001) were decreased in the HH group as compared to the control group and were increased in the HG group as compared to the HH group.

^bP < 0.001 vs Control,

^dP< 0.001 vs HH. Values are expressed as mean ± SEM (n = 7, each). Gln: Glutamine; Control: Control; HH: Hypobaric hypoxia group; HG: Hypobaric hypoxia plus Gln group.

Citation: Xu CL, Sun R, Qiao XJ, Xu CC, Shang XY, Niu WN. Protective effect of glutamine on intestinal injury and bacterial community in rats exposed to hypobaric hypoxia environment. World J Gastroenterol 2014; 20(16): 4662-4674
URL: https://www.wjgnet.com/1007-9327/full/v20/i16/4662.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i16.4662