Inflammation-related factors predicting prognosis of gastric cancer

Table 1 Important pathogens associated with the prognosis of gastric cancer

Factors	Source	Sample	Sample size	Cut-off value or characterization	Time of measurement	Prognostic role
H. pylori	Germany	Sera	166	Positivity	Prior to gastrectomy	Increased OS and RFS[17]
H. pylori	China	Tumor tissue	162	Positivity	At the time of surgery	Decreased OS and RFS[18]
H. pylori	Brazil	Tumor tissue	68	Positivity	At the time of surgery	No difference[19]
H. pylori	South Korea	Sera	274	Negativity	At the time of surgery and adjuvant chemotherapy	Decreased OS[20]
H. pylori	Italy	Sera and tumor tissue	297	Negativity	At the time of surgery	Decreased OS[21]
H. pylori	Brazilian, Asian and Caucasian	Sera	2454	Positivity	At the time of surgery	Increased OS and DFS[22]
EBV	Taiwan	Sera	150	Positivity	Prior to gastrectomy	Increased OS[27]
EBV	Korea	Sera	123	Expression	At the time of surgery	Increased OS and DFS[28]
EBV	Asia, Europe and Latin America	Sera	4599	Positivity	At the time of surgery	Increased OS[29]

DFS: Disease-free survival; EBV: Epstein-Barr virus; H. pylori: Helicobacter pylori; OS: Overall survival; RFS: Relapse-free survival.