Case-control study of factors that trigger inflammatory bowel disease flares

Table 1 Patient characteristics

	Flares (n = 66)	Controls (n = 68)	P value
Age (yr, mean ± SD)	49.0 ± 14.3	53.1 ± 15.7	0.09
Age at diagnosis (yr, mean ± SD)	37.7 ± 13.6	39.3 ± 15.1	0.68
Disease duration (yr, mean ± SD)	12.1 ± 10.4	14.2 ± 11.4	0.15
Sex (male/female)	59/7	63/5	0.56
Race
White	49 (74.2)	54 (79.4)	0.54
Black	15 (22.7)	12 (17.6)	0.52
Hispanic	2 (3.0)	2 (2.9)	1.00
Medication use
5-ASAs	50 (75.8)	54 (79.4)	0.68
Immunomodulators	17 (25.8)	30 (44.1)	0.03
Biologics	12 (18.2)	15 (22.1)	0.67
Antibiotics	0 (0)	0 (0)	-
Steroids	3 (4.5)	0 (0)	0.12
CD	33	30
Colonic disease	11 (16.7)	8 (11.8)	0.47
Ileal disease	9 (13.6)	7 (10.3)	0.60
Ileocolonic	12 (18.2)	15 (21.1)	0.67
UC	33	37
Extensive	18 (27.3)	19 (27.9)	1.00
Left-sided	15 (22.7)	13 (19.1)	0.67
Proctitis	1 (1.5)	5 (7.4)	0.21
Indeterminate colitis	0	1	1.00

CD: Crohn’s disease; UC: Ulcerative colitis.