Staging systems of hepatocellular carcinoma: A review of literature

Table 3 Comparison of different hepatocellular carcinoma staging system in the literature

Ref.	Country	Year	Case number	Patient population	The best
Levy et al[58]	Canada	2002	257	All	CLIP
Kudo et al[59]	Japan	2004	4525	All	JIS
Cillo et al[41]	Italy	2004	187	All	BCLC
Grieco et al[39]	Italy	2005	268	Early to intermediate	BCLC
Marrero et al[34]	United States	2005	244	All	BCLC
Nanashima et al[60]	Japan	2005	210	Surgery	CLIP
Huang et al[61]	Taiwan	2005	599	Surgery	TNM
Toyoda et al[62]	Japan	2005	1508	All	JIS
Pascual et al[63]	Spain	2006	115	All	BCLC
Georgiades et al[42]	United States	2006	172	TACE	Child-Pugh
Cillo et al[64]	Italy	2006	195	All	BCLC
Nanashima et al[65]	Japan	2006	230	Surgery	Modified JIS
Kondo et al[66]	Japan	2007	235	Surgery	JIS
Seong et al[67]	South Korea	2007	305	Radiotherapy	TNM
Chen et al[40]	Taiwan	2007	382	Surgery	CLIP
Huo et al[68]	Taiwan	2007	430	All	CLIP
Cammà et al[37]	Italy	2008	406	All	CLIP
Guglielmi et al[69]	Italy	2008	112	RFA	BCLC
Collette et al[70]	French	2008	538	Advanced	CLIP
Lu et al[71]	China	2008	234	Surgery	TNM
Chung et al[72]	Japan	2008	290	All	JIS
Lin et al[38]	Taiwan	2009	3668	All	CLIP
Hsu et al[36]	Taiwan	2010	1713	All	CLIP
Op den Winkel et al[73]	German	2012	405	Non-surgical	CLIP
Kim et al[35]	South Korea	2012	1717	All	BCLC

CLIP: Cancer of the Liver Italian Program; GRETCH: Groupe d’Etude et de Traitement du Carcinome Hépatocellulaire; BCLC: Barcelona Clinic Liver Cancer; CUPI: Chinese University Prognostic Index; JIS: Japan Integrated Staging Score; TNM: Tumor Node Metastasis.