Copyright
©2014 Baishideng Publishing Group Co.
World J Gastroenterol. Apr 14, 2014; 20(14): 3927-3937
Published online Apr 14, 2014. doi: 10.3748/wjg.v20.i14.3927
Published online Apr 14, 2014. doi: 10.3748/wjg.v20.i14.3927
Figure 1 Genetic and epigenetic alterations in gastric carcinogenesis.
The model for gastric carcinogenesis is presented based on genetic and epigenetic alterations. Methylation of the genes in blue appears to be involved in an epigenetic field defect. H. pylori: Helicobacter pylori; MSI: Microsatellite instability; EBV: Epstein-Barr virus; CIMP: CpG island methylator phenotype.
-
Citation: Yamamoto H, Watanabe Y, Maehata T, Morita R, Yoshida Y, Oikawa R, Ishigooka S, Ozawa SI, Matsuo Y, Hosoya K, Yamashita M, Taniguchi H, Nosho K, Suzuki H, Yasuda H, Shinomura Y, Itoh F. An updated review of gastric cancer in the next-generation sequencing era: Insights from bench to bedside and
vice versa . World J Gastroenterol 2014; 20(14): 3927-3937 - URL: https://www.wjgnet.com/1007-9327/full/v20/i14/3927.htm
- DOI: https://dx.doi.org/10.3748/wjg.v20.i14.3927