HLA variants related to primary sclerosing cholangitis influence rejection after liver transplantation

Table 7 Comparison of the frequencies of human leukocyte antigen-DRB1 alleles in the acute cellular rejection group (n = 23) and the non-acute cellular rejection group (n = 76) in the non- primary sclerosing cholangitis population

HLA-DRB1	Acute rejection		No acute rejection		OR	95%CI	Uncorrected
allele	n (alleles)	(%)	n (alleles)	(%)			P value
*01	7	(15.2)	18	(11.8)	1.4	0.6-3.4	0.55
*02	8	(17.4)	23	(15.1)	1.2	0.5-2.8	0.46
*03	13	(28.2)	24	(15.8)	2.5	1.9-5.4	0.05
*04	3	(6.5)	35	(23.0)	0.3	0.1-0.9	0.02
*07	6	(13.0)	12	(7.9)	1.8	0.7-4.8	0.29
*08	2	(4.3)	10	(6.6)	0.7	0.2-2.7	0.73
*10	0	(0)	3	(2.0)	0.5	0.1-4.2	0.59
*11	1	(2.2)	6	(3.9)	0.7	0.1-3.7	1.00
*12	1	(2.2)	3	(2.0)	1.4	0.2-7.9	0.93
*13	7	(15.2)	15	(9.9)	1.7	0.7-4.2	0.31
*14	0	(0)	3	(2.0)	0.5	0.1-4.2	1.00

OR and corresponding 95%CIs were calculated using Woolf’s formula with Haldane’s correction. Uncorrected P value is calculated by the χ² test or the Fisher’s exact test where appropriate. HLA: Human leukocyte antigen.