HLA variants related to primary sclerosing cholangitis influence rejection after liver transplantation

Table 4 Frequencies of human leukocyte antigen-DRB1 alleles in the acute cellular rejection group (n = 40) and the non-AR group (n = 103) in the total population

HLA-DRB1	Acute rejection		No acute rejection		OR	95%CI	Uncorrected
allele	n (alleles)	(%)	n (alleles)	(%)			P value
*01	10	(12.5)	23	(11.2)	1.2	0.5-2.5	0.75
*02	15	(18.8)	31	(15.0)	1.3	0.7-2.6	0.44
*03	25	(31.3)	40	(19.4)	1.9	1.0-3.3	0.03
*04	4	(5.0)	46	(22.3)	0.2	0.1-0.5	0.001
*07	7	(8.8)	16	(7.8)	1.2	0.5-2.8	0.78
*08	2	(2.5)	12	(5.8)	0.5	0.1-1.8	0.20
*09	0	(0)	1	(0.5)	0.9	0.1-9.5	0.72
*10	1	(1.3)	4	(1.9)	0.8	0.2-4.4	0.57
*11	1	(1.3)	6	(2.9)	0.6	0.1-2.9	0.37
*12	1	(1.3)	3	(1.5)	1.1	0.2-6.1	0.69
*13	13	(16.3)	21	(10.2)	1.7	0.8-3.6	0.16
*14	1	(1.3)	3	(1.5)	1.1	0.2-6.1	0.69

OR and corresponding 95%CI were calculated using Woolf’s formula with Haldane’s correction; uncorrected P value is calculated by the χ² test or the Fisher’s exact test where appropriate. HLA: Human leukocyte antigen.