HLA variants related to primary sclerosing cholangitis influence rejection after liver transplantation

Table 2 Frequencies of human leukocyte antigen-B alleles in the acute cellular rejection group (n = 40) and the non-acute cellular rejection group (n =102) in the total population (missing n = 1)

HLA-B allele	Acute rejection		No acute rejection		OR	95%CI	Uncorrected
	n (alleles)	(%)	n (alleles)	(%)			P value
*05	0	(0)	8	(4)	0.1	0.0-1.1	0.070
*07	10	(13)	23	(11)	1.2	0.6-2.5	0.690
*08	27	(34)	34	(17)	2.5	1.4-4.6	0.002
*12	12	(14)	27	(13)	1.2	0.6-2.3	0.700
*13	1	(1)	5	(2)	1.1	0.3-4.6	1.000
*14	2	(2)	4	(2)	1.1	0.3-4.6	1.000
*15	6	(7)	28	(14)	0.5	0.2-1.2	0.150
*16	1	(1)	4	(2)	0.7	0.1-3.4	0.510
*17	1	(1)	6	(3)	0.6	0.1-2.8	0.410
*18	1	(1)	6	(3)	0.4	0.1-2.0	0.240
*21	0	(0)	2	(1)	0.5	0.1-4.8	0.360
*22	3	(3)	2	(1)	3.6	0.8-16.4	0.120
*27	4	(5)	10	(5)	1.1	0.4-3.2	1.000
*35	4	(6)	19	(9)	0.7	0.3-1.8	0.230
*37	4	(5)	4	(2)	2.6	0.7-9.1	0.180
*40	4	(5)	19	(9)	0.6	0.2-1.5	0.220
*41	1	(1)	2	(1)	1.5	0.3-9.1	0.870
*47	0	(0)	1	(0.5)	0.8	0.1-9.2	0.530

OR and corresponding 95%CI were calculated using Woolf’s formula with Haldane’s correction; uncorrected P value: calculated by the χ² test or the Fisher’s exact test where appropriate. HLA: Human leukocyte antigen; AR: Acute cellular rejection.