Clinicopathological study of primary biliary cirrhosis with interface hepatitis compared to autoimmune hepatitis

Figure 5 Correlation between scores for necroinflammation and infiltrating mononuclear cells positive for CD3, CD4, CD8, and CD38 in primary biliary cirrhosis with interface hepatitis and autoimmune hepatitis. A: In primary biliary cirrhosis (PBC), the degree of CD3+ mononuclear cell infiltration and the scores of interface hepatitis and lobular hepatitis showed positive correlations; B: In autoimmune hepatitis (AIH), the degree of CD3+ mononuclear cell infiltration and the scores of interface hepatitis showed positive correlation, whereas that of CD3+ mononuclear cell infiltration and lobular hepatitis failed to correlate positively; C: In PBC, the degree of CD4+ mononuclear cell infiltration and the scores of interface hepatitis and lobular hepatitis showed positive correlations; D: In AIH, the degree of CD4+ mononuclear cell infiltration and the scores of interface hepatitis showed a positive correlation, whereas that of CD4+ mononuclear cell infiltration and lobular hepatitis failed to correlate positively; E: In PBC, the degree of CD8+ mononuclear cell infiltration and the scores of interface hepatitis and lobular hepatitis showed positive correlations; F: In AIH, the degree of CD8+ mononuclear cell infiltration and the scores of interface hepatitis and lobular hepatitis showed positive correlations; G: In PBC, the degree of CD38+ mononuclear cell infiltration and the scores of interface hepatitis and lobular hepatitis showed positive correlations; H: In AIH, the degree of CD38+ mononuclear cell infiltration and the scores of interface hepatitis showed positive correlation, whereas that of CD38+ mononuclear cell infiltration and lobular hepatitis failed to correlate positively. Spearman’s rank correlation test in A-H.