Contrast-enhanced ultrasound in the diagnosis of nodules in liver cirrhosis

Figure 3 A 70-year-old man with intrahepatic cholangiocarcinoma detected during surveillance for hepatocellular carcinoma. A: Gray-scale ultrasound shows a hypoechoic mass in the liver; B: Contrast-enhanced ultrasound (CEUS) in the arterial phase obtained 14 s after contrast injection shows mild hypervascularity in the periphery of the mass (arrows); C: CEUS obtained at 19 s after contrast injection shows diffuse hypervascularity of the mass (arrows); D: The mass (arrows) shows rapid washout at 28 s after contrast injection. Biopsy revealed cholangiocarcinoma.