Lack of association between apolipoprotein C3 gene polymorphisms and risk of nonalcoholic fatty liver disease in a Chinese Han population

Table 3 Odds ratios for nonalcoholic fatty liver disease according to apolipoprotein C3 and patatin-like phospholipase domain-containing protein 3 genotypes and alleles in the study population

	Unadjusted model		Adjusted model
	OR (95%CI)	P value	OR (95%CI)	P value
APOC3 gene
-455TT	1		1
-455TC + CC	0.96 (0.70-1.32 )	0.82	1.06 (0.72-1.57 )	0.76
-482CC	1		1
-482CT + TT	0.90 (0.66-1.24 )	0.52	1.00 (0.68-1.48 )	1.00
PNPLA3 gene
CC	1		1
CG + GG	5.77 (4.03-8.27)	0.00	3.70 (2.44-5.60)	0.00

-455C vs T: OR (95%CI) = 1.00 (0.82-1.22): -482C vs T: OR (95%CI) = 0.99 (0.81-1.21); PNPLA3G vs C: OR (95%CI) = 2.00 (1.80-2.23). The multiple logistic regression model was adjusted for age, gender, body mass index, waist, weight and presence of hypertension and T2DM.