Clinicopathological study of primary biliary cirrhosis with interface hepatitis compared to autoimmune hepatitis

Table 1 Main clinicopathological features of primary biliary cirrhosis with interface hepatitis and autoimmune hepatitis

	PBC1 (n = 41)	AIH (n = 43)
Gender (male:female)	5:36	4:39
Age (yr, mean ± SD)	59.0 ± 13.3	61.7 ± 10.8
Laboratory data
Ratio of AMA(+) or M2(+) and titer of AMA	75% and 141.2 ± 211.4	7% and 0 ± 0
Ratio of ANA(+) and titer2	72% and 724.3 ± 1262.4	91% and 411.1 ± 550.8
AST (IU/L)	51.6 ± 29.7	219.5 ± 180.5
ALT (IU/L)	54.0 ± 40.5	261.8 ± 253.4
ALP (IU/L)	615.5 ± 572.8	449.9 ± 251.8
IgG (mg/dL)	1832.9 ± 607.2	2246.2 ± 673.0
IgM (mg/dL)	300.9 ± 220.6	193.7 ± 120.0
IgA (mg/dL)	307.9 ± 122.4	387.2 ± 183.1

Laboratory data is shown as the mean ± SD; anti-mitochondrial antibodies (AMA)(+) ≥ 40; M2(+) ≥ 5; antinuclear antibodies (ANA)(+) ≥ 40.

¹With interface hepatitis;

²The average titer of ANA was higher in primary biliary cirrhosis (PBC) than in autoimmune hepatitis (AIH) because two PBC cases had a titer of 5120, which influenced the average. AST: Aspartate aminotransferase; ALT: Alanine aminotransferase; ALP: Alkaline phosphatase.