Multipotent role of platelets in inflammatory bowel diseases: A clinical approach

Table 2 Mean platelet volume correlations with clinical and laboratory parameters in inflammatory bowel disease patients

Ref.	Disease (n)	HC (n)	MPV correlations
Yüksel et al[41]	UC (61)	27	Reduced MPV in UC compared to HC
			Inverse correlation between MPV and disease activity
			Inverse correlation between MPV and disease extent
Järemo et al[39]	UC (18),	12	Reduced MPV in UC patients compared to HC
	CD (9)		Inverse correlation between MPV and disease activity
Güçlü et al[42]	UC (41)	(-)	Reduced MPV in active compared to non-active disease
Voudoukis et al[46]	UC (91), CD(107)	102	Reduced MPV in IBD patients compared to HC Correlation of MPV with Hb and sTfR
Öztürk et al[45]	UC (103), CD (72)	40	Reduced MPV in IBD compared to HC
			MPV decreases after remission in UC
			MPV increases after remission in CD
Kapsoritakis et al[40]	UC (93), CD (66)	38	Correlation between MPV and disease activity indices
			Correlation between MPV and disease extent
Kayahan et al[44]	UC (37)	20	Correlation between MPV and disease activity indices
			Reduced MPV in UC compared to HC
Liu et al[43]	CD (61)	50	Reduced MPV in CD patients compared to HC
			MPV value did not correlate to disease activity

CD: Crohn’s disease; Hb: Hemoglobin; HC: Healthy controls; IBD: Inflammatory bowel diseases; MPV: Mean platelet volume; sTfR: Soluble transferrin receptor; UC: Ulcerative colitis.