Role of stereotactic body radiation therapy for hepatocellular carcinoma

Table 1 Eligibility criteria for different treatment modalities

	Surgery	Percutaneous ablative therapy	TACE	SBRT
Tumor size	< 5 cm (or more)	< 3 cm	> 3-5 cm	4 (or 5) cm
Number of tumors	< 3	Depends on location	1-multiple (> 4)	< 1-3
Location or characteristics	Depends on liver function	Away from large vessels or biliary system	Hypervascular lesions	Away from bowels
Local control (2 yr)	> 90%	> 90%	< 65%	> 90%
Level of evidence	High	Intermediate-high	Intermediate-high	Low
Invasiveness	High	Less	Less	None
Damage to the liver	High	Low	Low-moderate	Low-moderate

SBRT: Stereotactic body radiation therapy; TACE: Transarterial chemoembolization.