Mass spectrometry-based serum peptide profiling in hepatocellular carcinoma with bone metastasis

Table 3 Sequences of significant differential peptides

m/za	m/zb	Delta mass	Peptide sequence	Protein name	Accession number
1780.7	1779.8952	0.8048	GEYYLQNAFLVAYTK	Alpha-fetoprotein	IPI00022443
1866.5	1866.8657	-0.3657	TATSEYQTFFNPRTFG	Prothrombin	IPI00019568
2131.6	2131.9237	-0.3237	NLPSDSQDLGQHGLEEDFM	Serglycin	IPI00019372
2880.4	2880.4904	-0.0904	RPGVLSSRQLGLPGPPDVPDHAAYHPF	Isoform 2 of inter-alpha-trypsin inhibitor heavy chain H4	IPI00218192
1532.4	1532.8213	-0.4213	CSRDNTLKVIDLR	Isoform 1 of autophagy-related protein 16-2	IPI00300536
2489.8	2489.2810	0.5190	YTIAALLSPYSYSTTAVVTNPKE	Transthyretin	IPI00022432
2234.3	2235.1993	-0.8993	KREEAPSLRPAPPPISGGGYR	Fibrinogen beta chain	IPI00298497

m/z^a: Mass to charge ratio of the peptide observed in matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF-MS); m/z^b: Mass to charge ratio of the peptide observed in LC-MS; Delta mass: The difference of the mass of peptide observed in MALDI-TOF-MS and LC-MS; Peptide sequence: The amino sequence of the peptide; Protein name: The full description of the protein that contained the peptide; Accession number: The accession number of the protein from the international protein index database.