Hyperoxia accelerates progression of hepatic fibrosis by up-regulation of transforming growth factor-&beta; expression

doi:10.3748/wjg.v20.i11.3011

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Mar 21, 2014; 20(11): 3011-3017
Published online Mar 21, 2014. doi: 10.3748/wjg.v20.i11.3011

Table 3 Quantitative real-time reverse-transcriptase polymerase chain reaction results

Measurement	Control group	Hypoxia group	Hyperoxia group
TGF-β mRNA average Ct	31.51 ± 1.49	30.84 ± 1.07	29.57 ± 0.96
β-actin mRNA average Ct	23.99 ± 1.18	23.35 ± 1.27	22.90 ± 0.72
^ΔCt	7.52 ± 0.63	7.49 ± 0.65	6.67 ± 0.67
^ΔΔCt	0 ± 0.63	-0.03 ± 0.65	-0.77 ± 0.74
Normalized expression ratio	1.0	1.1¹	1.9²

¹P = 1.000 vs control group,

²P = 0.027 vs control group.

Citation: Lee SH, Do SI, Kim HS. Hyperoxia accelerates progression of hepatic fibrosis by up-regulation of transforming growth factor-β expression. World J Gastroenterol 2014; 20(11): 3011-3017
URL: https://www.wjgnet.com/1007-9327/full/v20/i11/3011.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i11.3011