Frequency and prognostic role of mucosal healing in patients with Crohn’s disease and ulcerative colitis after one-year of biological therapy

Table 2 Univariate regression analysis of need for retreatment with biologicals

Factor	CD-P value	UC-P value
Gender	0.98	0.57
Disease duration	0.09	0.12
Smoking status	0.99	0.37
Appendectomy	0.99	-
Location/extent	0.99	0.81
Behaviour	0.99	-
Type of anti TNF-α therapy	0.73	-
Extraintestinal manifestations	0.35	-
Steroid therapy at inclusion	0.15	0.09
Previous surgery	0.99	-
Previous biological therapy	0.38	-
Elevated CRP level	0.47	0.97
Combined immunomodulator use	0.22	0.59
Outcome of induction therapy	0.30	0.29

TNF-α: Tumor necrosis factor-α; CD: Crohn’s disease; UC: Ulcerative colitis; CRP: C-reactive protein.