S-1-based combination therapy vs S-1 monotherapy in advanced gastric cancer: A meta-analysis

Table 2 Characteristics of patients

	Wasaburo 2008		Yoshito 2011		Hiroyuki 2011		Wang 2013
	S-1-based	S-1	S-1-based	S-1	S-1-based	S-1	S-1-based	S-1
Sex
Men	108	116	34	37	110	127	32	30
Women	40	34	14	10	45	33	9	11
Age, yr
Median	62	62	70	63	63	63	63	61
Rang	33-74	28-74	47-78	24-76	33-75	27-75	35-74	31-73
ECOG performances status
0	106	106	38	35	102	109	31	29
1	38	39	10	12	48	46	6	9
2	4	5	NA	NA	5	5	4	3
Body surface area, m2
< 1.25	6	4	3	1	NA	NA	2	3
1.25-1.50	64	63	19	18	NA	NA	19	17
> 1.50	79	83	26	28	NA	NA	20	21
Disease status
Unresectable	118	119	33	33	129	133	NA	NA
Recurrent	30	31	15	14	26	27	NA	NA
Histology
Diffuse type	103	89	25	25	93	88	28	30
Intestinal type	45	60	22	20	61	71	11	10
Other not specified	0	1	1	2	1	1	2	1
Primary tumor
No	53	58	NA	NA	62	67	15	17
Yes	95	92	NA	NA	93	93	26	24

NA: Not applicable; S-1-based: S-1-based combination therapy.