Controlled low central venous pressure reduces blood loss and transfusion requirements in hepatectomy

Table 3 Patient harm

Ref.	Harm measure	Results
Liu et al[15] 2008	Renal function	No significant differences in BUN and Cr on pre- and post-operative d 1, 3 and 7 between LCVP and control group. Values all within the normal range in both groups
Wang et al[16] 2006	Liver and renal function	There were no significant differences in ALT, TBIL, and Cr on post-operative d 1, 3, and 7 between the two groups. BUN was significantly higher in the control group than in the LCVP group, but was within the normal range in both groups
	Post-operative morbidity	Post-operative complications included biliary fistula, gastrointestinal bleeding, pleural effusion and subphrenic fluid collection, with an incidence of 20% (5/25) in the LCVP group and 24% (6/25) in the control group
Kato et al[17] 2008	Renal function	There were no significant intergroup differences in the values of BUN and creatinine on postoperative 1, 3, and 5 d
	Postoperative morbidity and mortality	There was no morbidity related to IVC clamping and no mortality in the two groups
Liu et al[18] 2005	Renal functionHemodynamic stability	No significant differences in BUN and Cr at postoperative 24 h between the two groups. Systolic blood pressures in the LCVP group were lower than those in the control group
El-Kharboutly et al[19] 2004	Not reported	Not reported

LCVP: Low central venous pressure; IVC: Infrahepatic vena cava; BUN: Blood urea nitrogen.