An accurate predictor of liver failure and death after hepatectomy: A single institution’s experience with 478 consecutive cases

Table 4 Univariate analysis of factors associated with the hepatic damage score (n = 478)

Variable	Group 1 (n = 380)	Group 2 (n = 98)	t	χ2	P value
Age (yr)	47.5 ± 12.4	46.2 ± 11.4	0.946		0.345
Gender				0.639	0.424
Male	306	83
Female	72	15
TBIL (µmol/L)1	17.5 ± 6.2	18.6 ± 5.7	-1.516		0.130
ALB (g/L)1	40.0 ± 5.0	39.6 ± 5.0	0.737		0.462
ALT (IU/L)1	55 ± 47	54 ± 30	0.117		0.907
AST (IU/L)1	60 ± 54	64 ± 41	-0.557		0.578
CREA (µmol/L)1	0.92 ± 0.28	0.94 ± 0.27	-0.692		0.489
ICG R15 (%)1	7.2 ± 4.3	8.7 ± 5.5	-2.598		0.010
INR1	1.09 ± 0.10	1.07 ± 0.11	1.305		0.192
HBsAg1				0.201	0.654
Positive	268	72
Negative	112	26
CTP grade1				7.735	0.007
A	351	81
B	29	17
MELD score1	5.8 ± 3.8	6.2 ± 3.4	-0.981		0.327
IBL (mL)	731 ± 790	972 ± 953	-2.309		0.022
IBT (mL)	427 ± 764	649 ± 943	-2.157		0.033
RS	2.4 ± 1.0	3.8 ± 1.4	-9.852		2. 0e-17

¹All parameters were measured one day before liver resection. BIL: Total bilirubin; ALB: Albumin; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; CREA: Creatinine; ICG-R15: The indocyanine green retention rate at 15 min; INR: International normalized ratio; HBsAg: Hepatitis B surface antigen; CTP: Child-Turcotte-Pugh; MELD: Model for end-stage liver disease; IBL: Intraoperative blood loss; IBT: Intraoperative blood transfusion; RS: Resected segments.