Adjuvant chemotherapy, p53, carcinoembryonic antigen expression and prognosis after D2 gastrectomy for gastric adenocarcinoma

Table 2 p53 tumor status, carcinoembryonic antigen tumor status and clinicopathological parameters n (%)

Characteristic	p53(+) (n = 222)	CEA(+) (n = 255)
Age (yr)	P = 0.406	P = 0.056
< 70	177 (76.6)	202 (87.4)
≥ 70	45 (81.8)	53 (96.4)
Sex, n	P = 0.804	P = 0.227
Men	156 (77.2)	183 (90.6)
Women	66 (78.6)	72 (85.7)
Tumor location	P = 0.271	P = 0.040
Proximal	135 (79.9)	156 (92.3)
Distal	87 (74.4)	99 (84.6)
Histological grade	P = 0.248	P = 0.248
High differentiation	4 (100)	4 (100)
Moderate differentiation	48 (71.6)	63 (94.0)
Low differentiation	170 (79.1)	188 (87.4)
Gloss type	P = 0.041	P = 0.954
Protrusion	73 (69.5)	93 (88.6)
Ulcer	142 (82.1)	155 (89.6)
Infiltration	7 (87.5)	7 (87.5)
Tumor size	P = 0.684	P = 0.103
< 5 cm	70 (76.1)	86 (93.5)
≥ 5 cm	151 (78.2)	168 (87.0)
T category	P = 0.420	P = 0.883
T1	2 (100)	2 (100)
T2	19 (70.4)	25 (92.6)
T3	165 (79.7)	184 (88.9)
T4	36 (72.0)	44 (88.0)
N category	P = 0.923	P = 0.198
N0	54 (79.4)	57 (83.8)
N1	38 (79.2)	45 (93.8)
N2	50 (78.1)	60 (93.8)
N3	80 (75.5)	90 (87.7)
AJCC stage (7th)	P = 0.211	P = 0.741
IIA	51 (76.1)	58 (86.6)
IIB	30 (81.1)	33 (89.2)
IIIA	58 (85.3)	63 (92.6)
IIIB	72 (75.0)	86 (89.6)
IIIC	11 (61.1)	15 (83.3)

CEA: Carcinoembryonic antigen.