Effect of aging on Kupffer cell membrane phospholipid function: Modulation by vitamin E

Table 3 Total inositol phospholipid in various age groups (mean ± SD, cpm × 1000, n = 5)

	6 mo	12 mo	18 mo	24 mo
NVEG
Control	48.5 ± 4.3	46.3 ± 4.5	39.5 ± 4.3a	30.8 ± 4.4b
LPS	52.4 ± 3.8	49.7 ± 5.6	42.8 ± 4.6a	34.8 ± 3.9b
PAF	78.7 ± 6.1f	78.1 ± 8.4f	62.9 ± 6.5bf	49.5 ± 5.4bf
VEG
Control	53.1 ± 4.0	56.2 ± 6.3	49.9 ± 5.0c	39.3 ± 2.9bc
LPS	51.8 ± 3.4	53.2 ± 4.9	48.8 ± 4.6	38.1 ± 4.0b
PAF	80.5 ± 7.3f	77.2 ± 8.1f	72.4 ± 6.8f	63.8 ± 6.4bdf

^aP < 0.05 compared with 6 mo;

^bP < 0.01 compared with 6 mo;

^cP < 0.05 compared with NVEG;

^dP < 0.01 compared with NVEG;

^fP < 0.001 compared with control. NVEG: non-VE pretreated group; VEG: VE pretreated group; LPS: Lipopolysaccharide; Platelet activating factor.