Overexpression and mutations of tumor suppressor gene p53 in hepatocellular carcinoma

Table 2 Correlations between p53 mutations and the clinicopathological features of Hepatocellular carcinoma

Clinicopathological features	Number ofcases	p53 expression (+)	p53 expression (-)	Significance
Tumor size (cm)
< 5	8	0	8
> 5	30	9	21
Classification
Trabecular	15	4	11
Pseudoglandular	16	3	13	b
Compact	7	2	7
Grade
I	3	0	3
II	7	1	6	c
III	15	2	13
IV	13	6	7
Metastasis
Positive	14	6	8
Negative	24	6	21	d

b: Not significant; a, c and d: P < 0.05.