Overexpression and mutations of tumor suppressor gene p53 in hepatocellular carcinoma

Table 1 Correlations between p53 overexpression and clinicopathological features of Hepatocellular carcinoma

Clinicopathological features	Number of cases	p53 expression(+)	p53 expression(-)	Significance
Tumor size (cm)
< 3	3	1	2
3-5	5	2	3	a
> 5	30	13	17
Classification
Trabecular	15	5	10
Pseudoglandular	16	8	8	b
Compact	7	3	4
Grade
I	3	1	2
II	7	2	5	c
III	15	5	10
IV	13	8	5
Metastasis
Positive	14	10	4
Negative	24	6	8	d

a and b: Significant; c and d: P < 0.05.