Clinical and experimental study on gastric mucosal pathology, gene expression, cAMP and trace elements of pixu patients

Table 5 Quantitative changes of cAMP, DNA, Zn, Cu, ZnO and CuO levels in gastric mucosa of the different spleen deficiency types and gastric diseases

		Deficiency of spleen energy	Spleen deficiency with energy stagnation	P value
Gastric cancer	cAMP	8.34 ± 1.23 (n = 8)	4.15 ± 1.36 (n = 14)	< 0.001
Benign gastric disease	cAMP	12.62 ± 1.87 (n = 20)	7.61 ± 1.84 (n = 15)	< 0.001
P value		< 0.001	< 0.001
Gastric cancer	DNA	26.54 ± 3.94 (n = 4)	36.11 ± 9.75 (n = 11)	< 0.05
Benign gastric disease	DNA	10.72 ± 0.92 (n = 15)	13.84 ± 3.52 (n = 9)	< 0.05
P value		< 0.05	< 0.01
Gastric cancer	Zn	1.60 ± 0.01 (n = 1)	1.24 ± 0.23 (n = 10)	< 0. 001
Benign gastric disease	Zn	3.19 ± 0.17 (n = 15)	2.40 ± 0.83 (n = 15)	< 0.001
P value		< 0.01	< 0.001
Gastric cancer	ZnO	0.71 ± 0.02 (n = 1)	0.27 ± 0.17 (n = 10)	< 0.001
Benign gastric disease	ZnO	1.57 ± 0.11 (n = 15)	1.18 ± 0.33 (n = 15)	< 0.001
P value		< 0.001	< 0.001
Gastric cancer	Cu	2.68 ± 0.03 (n = 1)	2.20 ± 0.57 (n = 10)	< 0.05
Benign gastric disease	Cu	4.66 ± 0.33 (n = 15)	3.63 ± 1.21 (n = 15)	< 0.01
P value		< 0.001	< 0.001
Gastric cancer	CuO	1.36 ± 0.03 (n = 1)	0.91 ± 0.19 (n = 10)	< 0.001
Benign gastric disease	CuO	2.51 ± 0.26 (n = 15)	1.91 ± 0.43 (n = 15)	< 0.001
P value		< 0.001	< 0.001