Clinical and experimental study on gastric mucosal pathology, gene expression, cAMP and trace elements of pixu patients

Table 4 Quantitative changes of cAMP, DNA, Zn, Cu, ZnO and CuO levels in gastric mucosa of the different intestinal metaplasia subtypes

		Complete	Incomplete	P value
Colonic intestinal metaplasia	cAMP	5.96 ± 0.42 (n = 9)	2.74 ± 0.64 (n = 13)	< 0.001
Small intestinal metaplasia	cAMP	12.31 ± 1.51 (n = 10)	6.78 ± 1.80 (n = 10)
P value		< 0.001	< 0.001
Colonic intestinal metaplasia	DNA	19.53 ± 9.55 (n = 6)	35.71 ± 9.79 (n = 117)	< 0.01
Small intestinal metaplasia	DNA	11.06 ± 0.99 (n = 9)	20.17 ± 4.78 (n = 4)
P value		< 0.01	< 0.05	< 0.01
Colonic intestinal metaplasia	Zn	1.77 ± 0.48 (n = 6)	1.25 ± 0.32 (n = 10)	< 0.05
Small intestinal metaplasia	Zn	2.82 ± 0.50 (n = 6)	2.06 ± 0.41 (n = 5)	< 0.05
P value		< 0.01	< 0.01
Colonic intestinal metaplasia	ZnO	0.57 ± 0.10 (n = 6)	0.25 ± 0.08 (n = 10)	< 0.001
Small intestinal metaplasia	ZnO	1.01 ± 0.20 (n = 6)	0.41 ± 0.16 (n = 5)	< 0.001
P value		< 0.001	< 0.05
Colonic intestinal metaplasia	Cu	2.78 ± 0.70 (n = 6)	2.11 ± 0.40 (n = 10)	< 0.05
Small intestinal metaplasia	Cu	3.86 ± 0.51 (n = 6)	3.11 ± 0.50 (n = 5)	< 0.05
P value		< 0.05	< 0.01
Colonic intestinal metaplasia	CuO	1.56 ± 0.13 (n = 6)	0.58 ± 0.05 (n = 10)	< 0.001
Small intestinal metaplasia	CuO	2.41 ± 0.43 (n = 6)	0.83 ± 0.21 (n = 5)	< 0.001
P value		< 0.001	< 0.001