Effect of thienorphine on intestinal transit and isolated guinea-pig ileum contraction

Figure 3 Effects of naloxone on the gastrointestinal propulsive activity in Kunming mice treated with thienorphine (0. 5 mg/kg), buprenorphine (0.5 mg/kg), or morphine (10 mg/kg). Gastrointestinal transit was expressed as % of the distance traveled by an orally administered marker relative to the total length of the small intestine over 15 min after marker administration. Each column and vertical bar represent the mean ± SE of 9-10 mice. ^aP < 0.05, ^bP < 0.001 vs intestinal transit without naloxone treatment. Thie: Thienorphine; Bup: Buprenorphine; Mor: Morphine.