CD24 expression predicts distant metastasis in extrahepatic bile duct cancer

Table 1 Clinicopathologic variables according to expression of CD24

Variables	Patients		P value
	CD24 (-)	CD24 (+)
	(n = 48)	(n = 36)
Age
≤ 60 yr	21	16	0.949
> 60 yr	27	20
Residual disease
R0	37	25	0.431
R1	11	11
Tumor location1
Proximal	30	29	0.077
Distal	16	6
T stage
T1-2	19	14	0.949
T3-4	29	22
N stage2
N0	33	15	0.036
N1	15	18
Histologic differentiation3
W/D	13	2	0.041
M/D	30	29
P/D	4	4
Use of maintenance chemotherapy
No	9	7	0.936
Yes	39	29

¹3 patients with tumor extending from the proximal to distal bile duct were excluded;

²In 3 patients, lymph node dissection was not performed;

³In 2 patients, the information on histologic differentiation was unavailable. R0: No microscopic residual disease; R1: Microscopic residual disease; W/D: Well differentiated; M/D: Moderately differentiated; P/D: Poorly differentiated.