Pre-treatment role of inosine triphosphate pyrophosphatase polymorphism for predicting anemia in Egyptian hepatitis C virus patients

doi:10.3748/wjg.v19.i9.1387

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Mar 7, 2013; 19(9): 1387-1395
Published online Mar 7, 2013. doi: 10.3748/wjg.v19.i9.1387

Table 2 Clinical and laboratory data according to rs1127354 inosine triphosphate pyrophosphatase genotypes (mean ± SD)

Criteria	CC	CA + AA	P value
Number, n (%)	93 (91.2)	9 (8.8)
Age (yr)	32.3 ± 7.3	34.4 ± 7.7	0.457
Sex (male/female)	82/11	8/1
BMI	25.4 ± 2.8	26.8 ± 1.6	0.046
Baseline Hb (g/dL)	14 ± 1.2	14.3 ± 1.03	0.441
plt (× 10³/μL)	233.2 ± 62.1	292.2 ± 74.3	0.046
WBCs (× 10³/μL)	6.2 ± 1.5	6.8 ± 1.1	0.172
ALT > ULN, n (%)	71 (76.3)	7 (77.7)	> 0.99
Creatinine level (mg/dL)	0.9 ± 0.46	0.98 ± 0.22	0.349
Baseline HCV RNA (log IU/mL)	5.46 ± 0.7	5.4 ± 0.8	> 0.99

Hb: Hemoglobin; BMI: Body mass index; plt: Platelet; WBCs: White blood cells; ALT: Alanine aminotransferase; ULN: Upper limit of normal of ALT = 12 IU/L; HCV: Hepatitis C virus.

Citation: Ahmed WH, Furusyo N, Zaky S, Sharaf Eldin A, Aboalam H, Ogawa E, Murata M, Hayashi J. Pre-treatment role of inosine triphosphate pyrophosphatase polymorphism for predicting anemia in Egyptian hepatitis C virus patients. World J Gastroenterol 2013; 19(9): 1387-1395
URL: https://www.wjgnet.com/1007-9327/full/v19/i9/1387.htm
DOI: https://dx.doi.org/10.3748/wjg.v19.i9.1387