Tumor suppressor function of ezrin-radixin-moesin-binding phosphoprotein-50 through β-catenin/E-cadherin pathway in human hepatocellular cancer

Figure 4 Ezrin-radixin-moesin-binding phosphoprotein-50 over-expression suppressed the migration and invasion of cancer cells. A: Migration and invasion analysis of parental (21.6 ± 1.3 cells/HP); B: pBK-CMV-HA (20.4 ± 1.1 cells/HP); C: pBK-CMV-HA-EBP50 (5.8 ± 0.8 cells/HP) cells with transwell assey; D: Analysis of the number of invasive cells; E: Apoptotic analysis of parental (3.4% ± 1.3%), pBK-CMV-HA (4.1% ± 1.5%) and pBK-CMV-HA-EBP50 (14.8% ± 2.7%) cells with flowcytometry. ^aP < 0.05, ^bP < 0.01 vs parental or pBK-CMV-HA.