Inhibition of pacemaker activity in interstitial cells of Cajal by LPS via NF-κB and MAP kinase

Figure 3 Effects of catalase on lipopolysaccharide-induced action in interstitial cells of Cajal. A: Pacemaker currents of interstitial cells of Cajal (ICCs) incubated at 37 °C with 200 μg/mL of lipopolysaccharide (LPS) for 12 h; B: Pacemaker currents in ICCs pretreated with catalase (3000 unit/mL) for 2 h prior to LPS incubation. The effects of catalase on the LPS-induced action in ICCs are summarized in C and D. Bars represent mean ± SE values (n = 4 per group).