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©2013 Baishideng Publishing Group Co.
World J Gastroenterol. Feb 28, 2013; 19(8): 1193-1199
Published online Feb 28, 2013. doi: 10.3748/wjg.v19.i8.1193
Published online Feb 28, 2013. doi: 10.3748/wjg.v19.i8.1193
Ref. | Patients included (n) | Portal hypertension-related variables studied | Outcome |
Llovet et al[3] | 43 | HVPG | CSPH independently associated with 5-yr post-operative mortality |
Bruix et al[12] | 29 | HVPG | CSPH independently associated with PLF at 3-mo |
Berzigotti et al[13] | 63 | Spleen size; platelet count; platelet count/spleen diameter; liver stiffness; LSPS PH risk score | Best single predictor of CSPH: liver stiffness; combination with spleen size and platelet count improved the results (AUROC LSPS 0.852; PH risk score 0.884) |
Boleslawski et al[14] | 43 | HVPG Platelet count; spleen size; esophageal varices = indirect signs of PH | CSPH independently associated with increased PLF and 90-d mortality. Indirect signs of PH showed no discriminative ability |
Capussotti et al[15] | 217 | Platelet count; spleen size; esophageal varices | PH associated with lower 3-yr and 5-yr survival |
Cescon et al[16] | 90 | Liver stiffness; platelet count; spleen size; esophageal varices | LS (but not other signs) independently associated with the risk of PLF |
Chen et al[17] | 190 | Intraoperative measurement of PVP | PVP independently associated with PLF on multivariate analysis |
Cucchetti et al[18] | 241 | Platelet count; spleen size; esophageal varices | PH associated with lower 3-yr and 5-yr survival, but not after adjusting for MELD, albumin and extent of resection no |
Figueras et al[19] | 39 | HVPG | CSPH associated with increased risk of morbidity |
Giuliante et al[20] | 588 | Platelet count; spleen size; esophageal varices | PH independently associated with increased mortality |
Imamura et al[21] | 532 | Varices, hypersplenism or hepatofugal portal flow | PH associated with a higher risk of post-operative ascites |
Ishizawa et al[22] | 203 | Platelet count | Platelet count < 100 × 103/mL independently associated with PLF |
Kim et al[23] | 72 | Liver stiffness | LS predicted PLF with good accuracy; LS better than ICG15 |
Llop et al[24] | 79 | Liver stiffness | CSPH predicted with good accuracy |
Ishizawa et al[25] | 434 | Platelet count; spleen size; esophageal varices | PH associated with lower 3-yr and 5-yr survival |
- Citation: Hernandez-Gea V, Turon F, Berzigotti A, Villanueva A. Management of small hepatocellular carcinoma in cirrhosis: Focus on portal hypertension. World J Gastroenterol 2013; 19(8): 1193-1199
- URL: https://www.wjgnet.com/1007-9327/full/v19/i8/1193.htm
- DOI: https://dx.doi.org/10.3748/wjg.v19.i8.1193