Accommodation and peristalsis are functional responses to obstruction in rat hypertrophic ileum

Figure 2 Motor responses to electrical field stimulation. Original tracings representing changes of intraluminal pressure of ileal segments in basal conditions and following subsequent application of a hydrostatic pressure of 5 cm H₂O (Low distens), EFS (30 V, 1 ms, 3 Hz, trains lasting 20 s every 120 s) and NANC conditions (NANC). A: Normal tissues; B: Control tissues; C: Hypertrophic tissues; D: Area under the pressure-time curve of motor responses in normal (N), control (C) and hypertrophic (H) ileal segments following subsequent application of a hydrostatic pressure of 5 cm H₂O (Low distens), EFS (30 V, 1 ms, 3 Hz, trains lasting 20 s every 120 s), NANC conditions (NANC), incubation with L-NAME 300 μmol/L (L-NAME) and incubation with α-chymotrypsin 10 IU/mL (α-chymo). Each value is the mean ± SE of 5 distinct experiments per group. ^bP < 0.01 vs corresponding normal values; ^cP < 0.05 vs corresponding control values; ^fP < 0.01; ^hP < 0.001; analysis of variance test followed by Bonferroni’s post-test.