Novel CDH1 germline mutations identified in Chinese gastric cancer patients

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Feb 14, 2013 (publication date) through Feb 15, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Feb 14, 2013; 19(6): 909-916
Published online Feb 14, 2013. doi: 10.3748/wjg.v19.i6.909

Table 4 Available clinical-pathologic characteristics of the gastric cancer cases with novel CDH1 mutations

ID code	Age onset (yr)	Gender	Family history	Histologic grade	Depth invasion (pT)	Lymph node involvement (pN)	Distant metastasis (M)	CDH1 variants
G45	66	Female	Sporadic	Poorly differentiated adenocarcinoma	pT3	pN3	M0	c.44_46delTGC
G68	51	Male	Sporadic	NA	NA	NA	NA	c.44_46delTGC
G150¹	58	Male	Sporadic	Moderately differentiated adenocarcinoma	pT2	pN3	M0	c.604G>A (V202I)
G26	56	Male	Sporadic	Moderately differentiated adenocarcinoma	pT3	pN2	M0	c.1320+7 A>G

¹Also harbors the MLH1 c.2101C>A (Q701K) mutation[16]. NA: Not available.

Citation: Chen QH, Deng W, Li XW, Liu XF, Wang JM, Wang LF, Xiao N, He Q, Wang YP, Fan YM. Novel CDH1 germline mutations identified in Chinese gastric cancer patients. World J Gastroenterol 2013; 19(6): 909-916
URL: https://www.wjgnet.com/1007-9327/full/v19/i6/909.htm
DOI: https://dx.doi.org/10.3748/wjg.v19.i6.909