Novel CDH1 germline mutations identified in Chinese gastric cancer patients

Table 2 Novel CDH1 mutations and polymorphism identified in Chinese gastric cancer patients n (%)

Gene location	Sequence variant	Consequence	Genotype
			Gastric cancer patients (n = 236)	Control (n = 240)	P value
5’UTR	c.-49 G>T	Substitution at the 5’UTR	4 (1.7)	3 (1.3)	0.723
Exon 1	c.44_46delTGC	Loss of the 15th code (Leu)	2 (0.85)	0 (0.0)	0.245
Exon 5	c.604G>A	Missense V202I	1 (0.4)	0 (0.0)	0.496
Intron 9	c.1320+7 A>G	Substitution of invariant A	1 (0.4)	0 (0.0)	0.496

Two-sided χ² test or Fisher's exact test for genotype distribution