Interleukin-17 plays a critical role in the acute rejection of intestinal transplantation

Figure 1 Expression levels of helper T cell 17 cells in intestine grafts paralleled with the degree of rejection in human recipients. The paraffin-embedded human intestine tissues after small bowel transplantation were sectioned and stained with hematoxylin eosin (HE), anti-rat-interleukin-17, and anti-rat-CD4 fluorescence antibodies (× 400). A-E: HE staining of intestine graft; F-J: Helper T cell 17 (Th17) immunofluorescence staining of intestine graft; A, F: No acute rejection; B, G: Suspicious acute rejection; C, H: Mild acute rejection; D, I: Moderate acute rejection; E, J: Severe acute rejection; K: Mean fluorescence intensity (MFI) of Th17 expression of intestine graft.