Desferrioxamine in warm reperfusion media decreases liver injury aggravated by cold storage

Figure 4 Iron release during warm ischemia and perfusion and effect of desferrioxamine on iron release. A: Iron release was measured in media after warm ischemia (WI) and at 1 and 2 h of perfusion from the control livers after 0.5 h of cold storage (CS0.5) and from the livers after 20 h of extended cold storage (CS20). Significantly different from the controls (mean ± SE, n = 5, ^aP < 0.05); B: Iron release was measured in media at 1 and 2 h of perfusion from livers following 20 h of cold storage (CS). Addition of desferrioxamine (DFO) to CS, WI and perfusion media is indicated by (+). Significantly different from 20 h of CS with no DFO (mean ± SE, n = 5, ^aP < 0.05).