Desferrioxamine in warm reperfusion media decreases liver injury aggravated by cold storage

Figure 3 Histopathological appearance of livers following cold storage, warm ischemia and perfusion and the effect of desferrioxamine. A: The control liver shows some early vacuolization in zone 2 following 0.5 h of cold storage (CS0.5) (magnified insert); B: Following 20 h of cold storage (CS20), the liver shows marked vacuolization and nuclear pyknosis in zones 3 as indicated by arrows (←, magnified insert); C: Following 20 h of CS with desferrioxamine (DFO) in CS, warm ischemia and perfusion media (CS WIP), the liver shows mild vacuolization in zone 3 (magnified insert). Hematoxylin and eosin staining and the original magnification was 100 ×. PT: Portal tract; CV: Central vein.