Transforming growth factor-β and toll-like receptor-4 polymorphisms are not associated with fibrosis in haemochromatosis

Table 8 Logistic regression analysis performed in subjects with HIC > 236 μmol/g dw and comparing outcome of F0 vs F3/4 (univariate analysis) (n = 47)

Factor	OR	95%CI	P value
Age	1.07	1.00-1.15	0.034
Alcohol	1.03	1.01-1.05	0.011
Female gender	0.27	0.05-1.55	0.140
MCP1	1.20	0.37-3.87	0.76
CCR2	0.74	0.13-4.12	0.73
TGFβ	0.58	0.09-3.52	0.553
hOGG1	1.50	0.47-4.77	0.492
IL10-1082	1.89	0.48-7.44	0.363
IL10-592	0.98	0.30-3.21	0.980
TLR4 299	1.17	0.77-7.79	0.868
TLR4 399	1.24	0.19-8.19	0.824

MCP-1: Monocyte chemoattractant protein 1; CCR-2: Chemokine C-C motif receptor; IL10: interleukin-10; TGF-β: Transforming growth factor-beta; TLR4: Toll-like receptor 4; hOGG1: Human 8-oxoguanine DNA glycosylase.