Transforming growth factor-β and toll-like receptor-4 polymorphisms are not associated with fibrosis in haemochromatosis

Table 4 Allele frequency in candidate genes assessed in patient and control groups by high resolution melt analysis: Compared to published data for Caucasian ethnicity populations

Gene	Patient group	Control group	Published results1
MCP1	A 0.729	A 0.736	A 0.695
	G 0.271	G 0.264	G0.305
CCR2	G 0.892	G 0.976	G 0.892
	A 0.108	A 0.024	A 0.108
TGFβ	G 0.918	G 0.892	G 0.887
	C 0.082	C 0.108	C 0.113
hOGG1	C 0.695	C 0.694	C 0.776
	G 0.305	G 0.306	G 0.224
IL10-1082	G 0.539	G 0.500	G0.531
	A 0.461	A 0.500	A 0.469
IL10-592	C 0.794	C 0.794	C 0.792
	A 0.206	A 0.206	A 0.208
TLR4 299	A 0.934	A 0.930	A 0.967
	G 0.066	G 0.070	G 0.033
TLR4 399	C 0.934	C 0.931	C 0.955
	T 0.066	T 0.069	T 0.045

¹NCBI dbSNP (HapMap CEU-Utah residents with Northern and Western European ancestry from the CEPH collection). MCP-1: Monocyte chemoattractant protein 1; CCR-2: Chemokine C-C motif receptor; IL10: Interleukin-10; TGF-β: Transforming growth factor-beta; TLR4: Toll-like receptor 4; hOGG1: Human 8-oxoguanine DNA glycosylase.