Anti-miRNA-221 sensitizes human colorectal carcinoma cells to radiation by upregulating PTEN

doi:10.3748/wjg.v19.i48.9307

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 19, Issue 48

This Article

Academic Content and Language Evaluation of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (6243)

All Articles published online

The chart showing PDF series, HTML series, Figures (1-6) series, Tables (1-2) series.

Item

Count

PDF

516

HTML

3667

Figures (1-6)

267

Tables (1-2)

200

Sum=4650

Publishing Process of This Article

The chart showing Browse series, Download series.

Item

Count

Browse

926

Download

667

Sum=1593

Dec 28, 2013 (publication date) through Nov 27, 2024

Times Cited of This Article

Times Cited (39)

Journal Information of This Article

Publication Name

World Journal of Gastroenterology

ISSN

1007-9327

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Original Article

World J Gastroenterol. Dec 28, 2013; 19(48): 9307-9317
Published online Dec 28, 2013. doi: 10.3748/wjg.v19.i48.9307

Table 2 Impact of PTEN on miR-221-mediated Caco2 cell radiosensitivity

Group	D₀	D_q	SF₄	SER
Blank control + irradiation	1.677	5.590	0.5667
Anti-PTEN-siRNA + irradiation	2.327	7.788	0.7569	0.718
Anti-miR-221 + irradiation	1.082	4.702	0.2977	1.550
Anti-miR-221 and anti-PTEN-siRNA + irradiation	1.511	5.010	0.4788	1.110

Caco2 cells were pretreated with anti-PTEN-siRNA for 24 h prior to the addition of anti-miR-221. D₀ and D_q were determined by standardized software, and the sensitization enhancement ratio (SER) was calculated by determining the ratio of the D₀ of the control group vs treated cells. SF₄: Surviving fraction at 4 Gy.

Citation: Xue Q, Sun K, Deng HJ, Lei ST, Dong JQ, Li GX. Anti-miRNA-221 sensitizes human colorectal carcinoma cells to radiation by upregulating PTEN. World J Gastroenterol 2013; 19(48): 9307-9317
URL: https://www.wjgnet.com/1007-9327/full/v19/i48/9307.htm
DOI: https://dx.doi.org/10.3748/wjg.v19.i48.9307