Hepatitis B virus subgenotype A1 predominates in liver disease patients from Kerala, India

doi:10.3748/wjg.v19.i48.9294

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 19, Issue 48

This Article

Academic Content and Language Evaluation of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (9162)

All Articles published online

The chart showing PDF series, HTML series, Figures (1-3) series, Tables (1-3) series.

Item

Count

PDF

473

HTML

5288

Figures (1-3)

379

Tables (1-3)

314

Sum=6454

Publishing Process of This Article

The chart showing Browse series, Download series.

Item

Count

Browse

1289

Download

1419

Sum=2708

Dec 28, 2013 (publication date) through Apr 3, 2025

Times Cited of This Article

Times Cited (26)

Journal Information of This Article

Publication Name

World Journal of Gastroenterology

ISSN

1007-9327

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Original Article

World J Gastroenterol. Dec 28, 2013; 19(48): 9294-9306
Published online Dec 28, 2013. doi: 10.3748/wjg.v19.i48.9294

Table 3 Summary of the pre-S mutations prevalent among the three clinical groups and genotypes

Isolate	Age/sex	Clinicalstatus	Subgenotype	PreS1	PreS2					Functionsaffected
				Start codon	Nucleotide from the EcoRI start			Amino acids from preS2 start codon
					Start codon	Deletion size	Position	Deletion size	Position
CHB42	40/M	CH	A1	ATG	ACG	-	-	-	-		A
HCC12	60/M	HCC	A1	ATG	ACG	-	-	-	-	A
HCC25	50/M	HCC	A1	ATG	ACG	-	-	-	-	A
CHB137	16/F	CH	A1	Deletion	ATG	18	2854-2871	6	1-6	I
CHB170	29/F	CH	D2	ATG	ATG	21	35-55	7	16-22	T, B, P
CHB202	33/M	CH	A1	ATG	ATG	24	28-51	8	13-21	T, B, P
CHB413	35/M	CH	A1	ATG	ATG	6	49-54	2	21-22	B, P
HCC29	50/F	HCC	A1	ATG	ATA	33	22-54	11	11-22	A, T, B, P
HCC30	32/M	HCC	A1	ATG	ATG	24	30-53	8	13-21	T, B, P
HCC37	30/F	HCC	A1	ATG	ATG	33	24-56	11	11-22	T, B, P
HCC39	55/M	HCC	A1	ATG	ATG	33	24-56	11	11-22	T, B, P
HCCT3	38/M	HCC	A1	ATG	ATA	54	1-54	18	4-22	A, T, B, P, M

A: PreS2 initiation codon abolished; M1T, M1I; I: PreS1 initiation start codon abolished; M: Morphogenesis domain ps1:103-119 and ps2: 1-4; T: T cell epitope ps1: 109-119/ps2: 1-13; B: B cell epitope, amino acids 14-26; P: Putative neutralizing anti-preS2 antibody, amino acids 1-26; HCC: Hepatocellular carcinoma; CHB: Chronic hepatitis B.

Citation: Gopalakrishnan D, Keyter M, Shenoy KT, Leena KB, Thayumanavan L, Thomas V, Vinayakumar K, Panackel C, Korah AT, Nair R, Kramvis A. Hepatitis B virus subgenotype A1 predominates in liver disease patients from Kerala, India. World J Gastroenterol 2013; 19(48): 9294-9306
URL: https://www.wjgnet.com/1007-9327/full/v19/i48/9294.htm
DOI: https://dx.doi.org/10.3748/wjg.v19.i48.9294