Effects of antiviral therapy on preventing liver tumorigenesis and hepatocellular carcinoma recurrence

Figure 1 Comparison of hepatocellular carcinoma recurrence and outcome in patients who received anti-hepatitis B virus therapy or placebo after hepatectomy or liver transplantation. A: From September 2009 to May 2010, 224 HCC patients who received partial hepatectomy due to HBV-related HCC were enrolled. HCC recurrence and 3-year overall survival rate in patients with anti-HBV treatment (n = 173) and patients without standardized anti-HBV treatment (n = 51) were monitored for at least 3 years. Left: log-rank test, P = 0.013; right: log-rank test, P = 0.006; B: From January 2010 to August 2011, 42 HCC patients within Milan criteria who received liver transplantation were enrolled. HCC recurrence and 2-year overall survival rate in patients with anti-HBV treatment (n = 28) and patients without standardized anti-HBV treatment (n = 14) are shown. Left: log-rank test, P = 0.031; right: log-rank test, P = 0.045. HCC: Hepatocellular carcinoma; HBV: Hepatitis B virus.