Intestinal stem cell marker LGR5 expression during gastric carcinogenesis

doi:10.3748/wjg.v19.i46.8714

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Dec 14, 2013; 19(46): 8714-8721
Published online Dec 14, 2013. doi: 10.3748/wjg.v19.i46.8714

Table 3 LGR5 expression in gastric cancer tissues of various differentiation n (%)

Tissue	LGR5 expression		P value
Tissue	Negative	Positive
Intestinal metaplasia	25 (27.8)	65 (72.2)	P value	0.000
Normal tissue	106 (73.1)	39 (26.9)
Dysplasia with IM			0.004
Yes	3 (18.8)	13 (81.2)
No	23 (62.2)	14 (37.8)
Lauren type			0.035
Intestinal	48 (41.4)	68 (58.6)
Diffuse/other	37 (57.8)	28 (42.2)
Intestinal type GC			0.019
Metastasis or recurrence	6 (12.5)	21 (31.3)
No metastasis or recurrence	42 (87.5)	46 (68.7)

LGR5: Leucine-rich repeat-containing G protein-coupled receptor 5; GC: Gastric cancer; IM: Intestinal metaplasia.

Citation: Zheng ZX, Sun Y, Bu ZD, Zhang LH, Li ZY, Wu AW, Wu XJ, Wang XH, Cheng XJ, Xing XF, Du H, Ji JF. Intestinal stem cell marker LGR5 expression during gastric carcinogenesis. World J Gastroenterol 2013; 19(46): 8714-8721
URL: https://www.wjgnet.com/1007-9327/full/v19/i46/8714.htm
DOI: https://dx.doi.org/10.3748/wjg.v19.i46.8714