Risk factors to predict severe postoperative pancreatic fistula following gastrectomy for gastric cancer

Table 3 Comparison of clinical factors between grade B and C postoperative pancreatic fistula according to International Study Group on Pancreatic Fistula classification n (%)

Variables		Total	ISGPF classification		1P value
			Grade B (n = 17)	Grade C (n = 18)
Sex	Male	30	14 (82)	16 (89)
	Female	5	3 (18)	2 (11)	0.944
Age (yr)	< 65	12	9 (53)	3 (17)
	65 ≤	23	8 (47)	15 (83)	0.0353
BMI (kg/m2)	< 21	13	9 (53)	4 (24)
	21 ≤	21	8 (47)	13 (76)	0.158
pT-stage	T1 T2	6	4 (24)	2 (11)
	T3 T4	29	13 (76)	16 (89)	0.402
pN-stage	N1 N2	21	9 (53)	12 (67)
	N3	14	8 (47)	6 (33)	0.629
pStage	III	9	5 (29)	4 (22)
	III IV	26	12 (71)	14 (78)	0.921
Splenectomy	Presence	21	11 (65)	10 (56)
	Absence	14	6 (35)	8 (44)	0.836
Pancreaticosplenectomy	Presence	12	4 (24)	8 (44)
	Absence	23	13 (76)	10 (56)	0.344
Lymphadenectomy	< D2	8	3 (18)	5 (28)
	D2 ≤	27	14 (82)	13 (72)	0.691
Resection status	R0	10	4 (24)	6 (33)
	R1	15	7(41)	8 (45)
	R2	10	6 (35)	4 (22)	0.892
Blood loss (g)	< 1000	23	11 (65)	12 (67)
	1000 ≤	12	6 (35)	6 (33)	0.815
Operation time (min)	< 330	19	10 (59)	9 (50)
	330 ≤	16	7 (41)	9 (50)	0.854
Preoperative Hb (g/dL)	<10	8	5 (29)	3 (17)
	10 ≤	27	12 (71)	15 (83)	0.443
Preoperative Alb (g/dL)	≤ 3.5	9	4 (27)	5 (29)
	3.5 <	23	11 (74)	12 (71)	0.825
2Lymphocyte counts (/mm3)	< 1400	26	9 (53)	17 (94)
	1400 ≤	9	8 (47)	1 (6)	0.0073

¹P values were derived from the χ² or Fisher's exact test and were considered significant at < 0.05;

²Lymphocyte counts at the diagnosis of postoperative pancreatic fistula;

³Significant values. ISGPF: International Study Group on Pancreatic Fistula; BMI: Body mass index.